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This fourth edition provides a comprehensive treatise on cysts occurring in the oral and maxillofacial regions, incorporating the latest advances in immunohistochemistry and molecular biology. It detailedly covers clinical features, epidemiology, radiology, pathogenesis, and pathology to support accurate diagnosis and treatment planning. The text serves as a seminal resource for professionals in oral pathology, medicine, surgery, and radiology. This updated volume reflects recent progress in human genetics to enhance the understanding of lesion etiology and pathogenesis.